The book has been designed as per the latest syllabus prescribed by Pharmacy Council of India (PCI). This book is specifically written with the intention of explaining the basic concepts of preclinical screening models in an easy to understand pattern by keeping the language as simple as possible. Main focus has been kept on the aspects of the students at undergraduate level in pharmacy courses as well as for the technocrats working in preclinical research area. This book may be one of the finest additions to the shelf that offers a wide range of basic concepts in the field of experimental pharmacology. Along with the basic concepts, the text enclosed in this book also point up the technical and practical aspects of the subject. This book will also be helpful for academicians, scientists, preclinical technocrats and the young pharmacologists.